Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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Quantity
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3,391
Tocris Bioscience™ Pladienolide B
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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mRNA splicing inhibitor; antitumor
3,392
Tocris Bioscience™ NMS 873
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Potent and selective p97 ATPase (VCP) allosteric inhibitor
| CAS | 1418013-75-8 |
|---|---|
| Chemical Name or Material | 3-[3-(Cyclopentylthio)-5-[[[2-methyl-4'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]oxy]methyl]-4H-1,2,4-triazol-4-yl]pyridine |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C27H28N4O3S2 |
| Formula Weight | Observed MW: 520.67 |
| Assay Percent Range | >98% |
3,393
Tocris Bioscience™ ci-IP3/PM
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Caged inositol triphosphate
3,394
Tocris Bioscience™ Brequinar sodium
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Potent and selective DHODH inhibitor.
| Target | DHODH Inhibitors |
|---|---|
| CAS | 96201-88-6 |
| Chemical Name or Material | 6-Fluoro-2-(2′-fluoro[1,1′-biphenyl]-4-yl)-3-methyl-4-quinolinecarboxylic acid sodium |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C23H14F2NO2Na |
| Formula Weight | Observed MW: 397.35 |
| Assay Percent Range | >99% |
3,395
Tocris Bioscience™ Pimonidazole
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Hypoxia detection reagent
| CAS | 70132-50-2 |
|---|---|
| Chemical Name or Material | α-[(2-Nitro-1H-imidazol-1-yl)methyl]-1-piperidineethanol |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C11H18N4O3 |
| Formula Weight | Observed MW: 254.29 |
| Assay Percent Range | >98% |
3,396
Tocris Bioscience™ Givinostat hydrochloride
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Histone deacetylase inhibitor
| CAS | 199657-29-9 |
|---|---|
| Chemical Name or Material | [6-[(Diethylamino)methyl]-2-naphthalenyl]methyl-N-[4-[(hydroxyamino)carbonyl]phenyl]carbamate hydrochloride |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C24H27N3O4.HCl |
| Formula Weight | Observed MW: 457.95 |
| Assay Percent Range | >98% |
3,397
Tocris Bioscience™ MD13
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Potent MIF Degrader (PROTAC™)
3,398
Tocris Bioscience™ BAY 58-2667 hydrochloride
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Potent soluble guanylyl cyclase (sGC) activator
3,399
Tocris Bioscience™ J 2156
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Selective high affinity human sst4 agonist
| CAS | 2387505-73-7 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | (1'S,2S)-4-Amino-N-(1'-carbamoyl-2'-phenylethyl)-2-(4"-methyl-1"-naphthalenesulfonylamino)butanamide trifluoroacetate |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C24H28N4O4S.C2HF3O2 |
3,400
Tocris Bioscience™ Filipin III
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Polyene antibiotic; inhibits formation of pathological isoform of prion protein
3,401
Tocris Bioscience™ FFN 206 dihydrochloride
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Fluorescent VMAT2 substrate
3,402
Tocris Bioscience™ Mexiletine hydrochloride
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CAS: 5376-10-3 Molecular Formula: C11H12N2O
| CAS | 5376-10-3 |
|---|---|
| Molecular Formula | C11H12N2O |
3,403
Tocris Bioscience™ Cyprodime hydrochloride
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CAS: 2387505-50-0 Molecular Formula: C22H30ClNO3
| CAS | 2387505-50-0 |
|---|---|
| Molecular Formula | C22H30ClNO3 |
3,404
Tocris Bioscience™ Carboplatin
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CAS: 41575-94-4 Molecular Formula: C6H12N2O4Pt
| CAS | 41575-94-4 |
|---|---|
| Molecular Formula | C6H12N2O4Pt |
3,405
Tocris Bioscience™ DAPT
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CAS: 208255-80-5 Molecular Formula: C23H26F2N2O4
| CAS | 208255-80-5 |
|---|---|
| Molecular Formula | C23H26F2N2O4 |